Cytochrome c Monolonal Antibody [7H8.2C12] (NHP-AB209)

• This product is an antibody that was generated by immunizing mouse against cytochrome C purified from horse. It is used only in in vitro assays.

Detailed Product Description

• Introduction: Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
• Conjugate: None
• Antibody Isotype: IgG2b
• Applications: IHC; WB

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Bovine; Guinea Pig; Hamster; Horse; Human; Monkey; Mouse; Pig; Rabbit; Rat; Sheep
• Immunogen: Cytochrome C purified from horse

Product Property

• Purification: Protein G Column
• Format: Liquid
• Concentration: 1 mg/mL
• Buffer: PBS, pH 7.2, 50% glycerol, 0.09% azide
• Storage: Short term: 4˚C. Long term: Store at -20˚C. Avoid freeze-thaw cycles.

Target Information

• Target: Cytochrome c
• Clone: 7H8.2C12
• Clonality: Monoclonal
• Alternative Names: Cytochrome c; Cytochrome C, expressed in somatic tissues; Cytochrome c, somatic; hc1
• Entrez Gene ID: 54205