Non-Human Primate (NHP) related Antibody Products, ,
Category: Non-Human Primate (NHP) related Antibody Products

HSP27 Monoclonal Antibody (HJ20) (NHP-AB154)

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Product Overview Detailed Product Description Technical Specifications Product Property Target Information Downloadable Resources Customer Reviews

This product is an antibody that was generated by immunizing mouse against purified human HSP27 (earlier called 24K) from breast cancer MCF-7 cells. It is used only in in vitro assays.

Introduction: In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins. HSPB1 (heat shock protein beta-1 or HSP27) is a small heat shock protein which functions as a molecular chaperone that maintains denatured proteins in a folding-competent state.
Conjugate: None
Antibody Isotype: IgG1κ
Applications: Flow Cytometry; IF; IHC; WB
Host Species: Mouse
Species Reactivity: Chicken; Chimpanzee; Human; Mouse; Rat; Sheep
Immunogen: Purified human HSP27 (earlier called 24K) from breast cancer MCF-7 cells
Purification: Protein G affinity chromatography
Format: Liquid
Concentration: 0.2 mg/mL
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Storage: Store at 4⁰C.
Target: HSP27
Clone: HJ20
Clonality: Monoclonal
Related Disease: Mutations in the gene can result in Charcot-Marie-Tooth disease 2F and Neuronopathy distal hereditary motor 2B.
Alternative Names: 28 kDa heat shock protein; DKFZp586P1322; epididymis secretory protein Li 102; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; heat shock 27kD protein 1; heat shock 27kDa protein 1; Heat shock protein; Heat shock protein beta-1; HS; HSP; HSP 27; HspB1; Phospho-HSP 27; SRP27; Stress-responsive protein 27
Entrez Gene ID: 3315
Function: It plays a role in stress resistance and actin organization. Through its molecular chaperone activity, HSP27 regulates numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.
  • HSP27 Monoclonal Antibody (HJ20) (NHP-AB154) Data Sheet: Detailed information. datasheet

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Fig.1 Obesity can be counteracted by gene regulation.

Your research is unique, and we understand that standard products may not always fit. Our team of experts specializes in custom NHP sample collections. We can design a tailored protocol to meet your specific research requirements, including samples with unique anticoagulant types, customized volumes, or from specific disease models.

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