Category:
Non-Human Primate (NHP) related Antibody Products
HSP27 Monoclonal Antibody (HJ20) (NHP-AB154)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing mouse against purified human HSP27 (earlier called 24K) from breast cancer MCF-7 cells. It is used only in in vitro assays.
Introduction
In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins. HSPB1 (heat shock protein beta-1 or HSP27) is a small heat shock protein which functions as a molecular chaperone that maintains denatured proteins in a folding-competent state.
Conjugate
None
Antibody Isotype
IgG1κ
Applications
Flow Cytometry; IF; IHC; WB
Host Species
Mouse
Species Reactivity
Chicken; Chimpanzee; Human; Mouse; Rat; Sheep
Immunogen
Purified human HSP27 (earlier called 24K) from breast cancer MCF-7 cells
Purification
Protein G affinity chromatography
Format
Liquid
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Storage
Store at 4⁰C.
Target
HSP27
Clone
HJ20
Clonality
Monoclonal
Related Disease
Mutations in the gene can result in Charcot-Marie-Tooth disease 2F and Neuronopathy distal hereditary motor 2B.
Alternative Names
28 kDa heat shock protein; DKFZp586P1322; epididymis secretory protein Li 102; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; heat shock 27kD protein 1; heat shock 27kDa protein 1; Heat shock protein; Heat shock protein beta-1; HS; HSP; HSP 27; HspB1; Phospho-HSP 27; SRP27; Stress-responsive protein 27
Entrez Gene ID
3315
Function
It plays a role in stress resistance and actin organization. Through its molecular chaperone activity, HSP27 regulates numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.
- HSP27 Monoclonal Antibody (HJ20) (NHP-AB154) Data Sheet: Detailed information. datasheet
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Your research is unique, and we understand that standard products may not always fit. Our team of experts specializes in custom NHP sample collections. We can design a tailored protocol to meet your specific research requirements, including samples with unique anticoagulant types, customized volumes, or from specific disease models.
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For research use only. Not intended for any clinical use.
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