HSPA14 Polyclonal Antibody (NHP-AB380)

• This product is an antibody that was generated by immunizing rabbit against recombinant fusion protein containing a sequence corresponding to amino acids 240-509 of human HSPA14 (NP_057383.2). It is used only in in vitro assays.

Detailed Product Description

• Introduction: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).
• Conjugate: None
• Antibody Isotype: IgG
• Applications: IF; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Monkey; Mouse
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-509 of human HSPA14 (NP_057383.2)

Product Property

• Purification: Affinity purification
• Format: Liquid
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Storage: Store at -20⁰C. Avoid freez-thaw cycles.

Target Information

• Clonality: Polyclonal
• Alternative Names: Heat shock 70 kDa protein 14; heat shock 70kDa protein 14; heat shock 70kDa protein 14 isoform 1 variant 3; Heat shock protein; heat shock protein 4; Heat shock protein HSP60; heat shock protein hsp70-related protein; heat shock protein, 70 kDa 4; HSP; HSP70-like protein 1; HSP7E; hsr.1; NST-1
• Entrez Gene ID: 51182