Category:
Non-Human Primate (NHP) related Antibody Products
HSPA14 Polyclonal Antibody (NHP-AB380)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against recombinant fusion protein containing a sequence corresponding to amino acids 240-509 of human HSPA14 (NP_057383.2). It is used only in in vitro assays.
Introduction
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).
Conjugate
None
Antibody Isotype
IgG
Applications
IF; WB
Host Species
Rabbit
Species Reactivity
Human; Monkey; Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 240-509 of human HSPA14 (NP_057383.2)
Purification
Affinity purification
Format
Liquid
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage
Store at -20⁰C. Avoid freeze-thaw cycles.
Clonality
Polyclonal
Alternative Names
Heat shock 70 kDa protein 14; heat shock 70kDa protein 14; heat shock 70kDa protein 14 isoform 1 variant 3; Heat shock protein; heat shock protein 4; Heat shock protein HSP60; heat shock protein hsp70-related protein; heat shock protein, 70 kDa 4; HSP; HSP70-like protein 1; HSP7E; hsr.1; NST-1
Entrez Gene ID
51182
- HSPA14 Polyclonal Antibody (NHP-AB380) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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