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- This product is an antibody that was generated by immunizing rabbit against a portion of amino acids 350-400 of human IKZF3. It is used only in in vitro assays.
Detailed Product Description
- Introduction: This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
- Conjugate: None
- Applications: IHC; WB
Technical Specifications
- Host Species: Rabbit
- Species Reactivity: Chimpanzee; Human; Monkey
- Immunogen: A portion of amino acids 350-400 of human IKZF3
Product Property
- Purification: Immunoaffinity Chromatography
- Format: Liquid
- Concentration: 0.5 mg/mL
- Buffer: PBS, 0.05% BSA, 0.05% sodium azide
- Storage: Short term: 4˚C. Long term: Store at -20˚C.
Target Information
- Clonality: Polyclonal
- Alternative Names: Ikaros family zinc finger protein 3; Zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos)
- Entrez Gene ID: 22806
Downloadable Resources
FAQs
Customer Reviews
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Q 1: What applications are IKZF3 Polyclonal Antibodies commonly used for in research?
A: They are widely used in studying immune system regulation and autoimmune diseases due to IKZF3's role in lymphocyte development and function.
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Q 2: How does the specificity of IKZF3 Polyclonal Antibodies impact experimental outcomes?
A: High specificity is crucial for accurate detection and quantification of IKZF3, impacting the reliability of research findings in immunology and cancer studies.
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High Specificity & High Reliability
The IKZF3 Polyclonal Antibody has been a cornerstone in our immunology research, providing exceptional specificity and reliability. Its contribution to our studies on lymphocyte differentiation has been invaluable. -
High Consistency & Good Quality
We've utilized the IKZF3 Polyclonal Antibody in several projects focusing on autoimmune diseases. The quality and consistency of the antibody have greatly enhanced our experimental outcomes, helping us to advance our research significantly.
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NHP Biologicals from Creative Biolabs are for research, diagnostic, or manufacturing purposes only. They may not be intended for or are not approved for any other use.
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