Category:
Non-Human Primate (NHP) related Antibody Products
KDR Polyclonal Antibody (NHP-AB393)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a peptide located near the internal domain of KDR (Human). It is used only in in vitro assays.
Introduction:
KDR, also known as vascular endothelial growth factor (VEGF), is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.
Conjugate:
None
Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Dog; Gibbon; Gorilla; Human; Monkey
Immunogen:
A peptide located near the internal domain of KDR (Human)
Purification:
Immunoaffinity Chromatography
Format:
Liquid
Concentration:
0.4 mg/mL
Buffer:
PBS, 0.1% sodium azide
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Alternative Names:
CD309; CD309 antigen; Fetal liver kinase 1; fetal liver kinase-1; FLK-1; KDR; Kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; tyrosine kinase growth factor receptor; Vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR-2
Entrez Gene ID:
3791
- KDR Polyclonal Antibody (NHP-AB393) Data Sheet: Detailed information. datasheet
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