Category:
Non-Human Primate (NHP) related Antibody Products
PTHR1 Monoclonal Antibody (L243) (NHP-AB243)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing mouse against a synthetic peptide corresponding to aa 146 - 169 of PTHR1 (Human). It is used only in in vitro assays.
Introduction
Parathyroid hormone receptor 1 is a member of the G-protein coupled receptor family. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Parathyroid hormone receptor 1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus.
Conjugate
None
Antibody Isotype
IgG1κ
Applications
IHC; WB
Host Species
Mouse
Species Reactivity
Bovine; Dog; Gibbon; Gorilla; Horse; Human; Monkey; Orangutan; Pig
Immunogen
A synthetic peptide corresponding to aa 146 - 169 of PTHR1 (Human)
Purification
Protein G Column
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS, pH 7.6, 0.07% sodium azide, 30% glycerol
Storage
Short term: 4˚C. Long term: Store at -20˚C. Avoid freeze-thaw cycles.
Clone
L243
Clonality
Monoclonal
Alternative Names
MGC138426; MGC138452; Parathyroid hormone 1 receptor; parathyroid hormone receptor; parathyroid hormone receptor 1; Parathyroid hormone/parathyroid hormone-related peptide receptor; parathyroid hormone/parathyroid hormone-related protein receptor; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTHrP-R; PTHrP-receptor; seven transmembrane helix receptor
Entrez Gene ID
5745
- PTHR1 Monoclonal Antibody (L243) (NHP-AB243) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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