PTHR1 Monoclonal Antibody (L243) (NHP-AB243)

• This product is an antibody that was generated by immunizing mouse against a synthetic peptide corresponding to aa 146 - 169 of PTHR1 (Human). It is used only in in vitro assays.

Detailed Product Description

• Introduction: Parathyroid hormone receptor 1 is a member of the G-protein coupled receptor family. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Parathyroid hormone receptor 1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus.
• Conjugate: None
• Antibody Isotype: IgG1κ
• Applications: IHC; WB

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Bovine; Dog; Gibbon; Gorilla; Horse; Human; Monkey; Orangutan; Pig
• Immunogen: A synthetic peptide corresponding to aa 146 - 169 of PTHR1 (Human)

Product Property

• Purification: Protein G Column
• Format: Liquid
• Concentration: 1 mg/mL
• Buffer: PBS, pH 7.6, 0.07% sodium azide, 30% glycerol
• Storage: Short term: 4˚C. Long term: Store at -20˚C. Avoid freeze-thaw cycles.

Target Information

• Clone: L243
• Clonality: Monoclonal
• Alternative Names: MGC138426; MGC138452; Parathyroid hormone 1 receptor; parathyroid hormone receptor; parathyroid hormone receptor 1; Parathyroid hormone/parathyroid hormone-related peptide receptor; parathyroid hormone/parathyroid hormone-related protein receptor; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTHrP-R; PTHrP-receptor; seven transmembrane helix receptor
• Entrez Gene ID: 5745