PKM Monoclonal Antibody (T3R12) (NHP-AB241)

• This product is an antibody that was generated by immunizing mouse against recombinant human PKM protein. It is used only in in vitro assays.

Detailed Product Description

• Introduction: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: IF; WB

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Human; Monkey; Mouse
• Immunogen: Recombinant human PKM protein

Product Property

• Purification: Affinity purification
• Format: Liquid
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Storage: Store at -20⁰C. Avoid freez-thaw cycles.

Target Information

• Clone: T3R12
• Clonality: Monoclonal
• Alternative Names: CTHBP; Cytosolic thyroid hormone-binding protein; epididymis secretory protein Li 30; m2pk; OIP-3; OPA-interacting protein 3; p58; PK, muscle type; Pyruvate kinase 2/3; pyruvate kinase 3; pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle isozyme; Pyruvate kinase PKM; THBP1; Thyroid hormone-binding protein 1; thyroid hormone-binding protein, cytosolic; Tumor M2-PK
• Entrez Gene ID: 5315