Category:
Non-Human Primate (NHP) related Antibody Products
LAG-3 (CD223) Monoclonal Antibody (SP38) (NHP-AB223)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing mouse against recombinant human LAG-3. It is used only in in vitro assays.
Introduction:
LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).
Conjugate:
None
Antibody Isotype:
IgG1
Applications:
ELISA; Func; ICC; IHC; IP; WB
Host Species:
Mouse
Species Reactivity:
Human; Monkey
Immunogen:
Recombinant human LAG-3
Purification:
SDS-PAGE
Format:
Liquid
Concentration:
0.5 mg/mL
Buffer:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Storage:
Store at -20⁰C for at least 1 year.
Target:
LAG-3
Clone:
SP38
Clonality:
Monoclonal
Alternative Names:
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; LAG-3; Lymphocyte activation gene 3 protein; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG-3; sLAG3; soluble LAG 3; lymphocyte activating 3; soluble LAG3
Entrez Gene ID:
3902
- LAG-3 (CD223) Monoclonal Antibody (SP38) (NHP-AB223) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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