Category:
Non-Human Primate (NHP) related Antibody Products
PDE8B Polyclonal Antibody (NHP-AB417)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against human leukocytes. It is used only in in vitro assays.
Introduction:
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the 5-prime,3-prime-cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been grouped into several families based on substrate affinities, inhibitor sensitivities, mode of regulation, and amino acid sequence homologies. The PDE8 family contains high-affinity cAMP-specific, IBMX (3-isobutyl-1-methyl-xanthine)-insensitive PDEs, such as PDE8B. All PDEs share a conserved C-terminal catalytic region and a variable N-terminal domain that presumably accounts for the distinctive regulatory properties unique to the individual families.
Conjugate:
None
Applications:
IHC
Host Species:
Rabbit
Species Reactivity:
Gibbon; Gorilla; Human; Monkey
Immunogen:
A peptide located near the internal domain of PDE8B (Human)
Purification:
Immunoaffinity Chromatography
Format:
Liquid
Concentration:
0.3 mg/mL
Buffer:
PBS, 0.1% sodium azide
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Alternative Names:
3',5' cyclic nucleotide phosphodiesterase 8B; Cell proliferation-inducing gene 22 protein; FLJ11212; High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; HsPDE8B
Entrez Gene ID:
8622
- PDE8B Polyclonal Antibody (NHP-AB417) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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