Category:
Non-Human Primate (NHP) related Antibody Products
Perlecan Monoclonal Antibody (BR1C1) (NHP-AB240)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing mouse against a murine EHS laminin. It is used only in in vitro assays.
Introduction:
Perlecan is a major heparan-sulfate proteoglycan (HSPG) found within all basement membranes and cell surfaces. Because of its strategic location and ability to store and protect growth factors, perlecan has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a coreceptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
Conjugate:
None
Antibody Isotype:
IgG2aκ
Applications:
Flow Cytometry; IF; IHC-P
Host Species:
Rat
Species Reactivity:
Bovine; Fish; Monkey; Mouse; Pig
Immunogen:
A murine EHS laminin
Purification:
Protein G affinity chromatography
Format:
Liquid
Concentration:
0.2 mg/mL
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Storage:
Store at 4⁰C. Avoid freeze-thaw cycles.
Clone:
BR1C1
Clonality:
Monoclonal
Alternative Names:
Basement membrane-specific heparan sulfate proteoglycan core protein; Endorepellin; endorepellin (domain V region); HSPG; LG3 peptide; Perlecan; perlecan proteoglycan; PLC; RP11-132G19.2
Entrez Gene ID:
3339
- Perlecan Monoclonal Antibody (BR1C1) (NHP-AB240) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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