IL-4 Monoclonal Antibody (R4LA), Biotin (NHP-AB136)

• This product is an antibody that was generated by immunizing rat against CHO-expressed human IL-4. It is used only in in vitro assays.

Detailed Product Description

• Introduction: Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
• Conjugate: Biotin
• Antibody Isotype: IgG1
• Applications: Flow Cytometry

Technical Specifications

• Host Species: Rat
• Species Reactivity: Baboon; Human
• Immunogen: CHO-expressed human IL-4

Product Property

• Format: Liquid
• Concentration: 0.5 mg/mL
• Buffer: Supplied in PBS/NaN3
• Storage: Store at 4⁰C.

Target Information

• Target: IL-4
• Clone: R4LA
• Clonality: Monoclonal
• Alternative Names: B-cell growth factor 1; B-cell IgG differentiation factor; B-cell stimulatory factor 1; BSF-1; H-IL-4; IGG1 induction factor; IL-4; ILN; Interleukin; Interleukin-4; Interleukin4; Lymphocyte stimulatory factor 1; M-IL-4; MGC79402
• Entrez Gene ID: 3565