Category:
Non-Human Primate (NHP) related Antibody Products
TRPV2 Polyclonal Antibody (NHP-AB481)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a peptide located in the N-Terminal domain of TRPV2 (Human). It is used only in in vitro assays.
Introduction
TRPV2 is a calcium-permeable, non-selective cation channel with an outward rectification, that seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. VRL-1 does not respond to capsaicin, acid, or moderate heat, but instead is activated by high temperatures, with a threshold of approximately 52 degrees C. Within sensory ganglia, TRPV2 is most prominently expressed by a subset of medium- to large-diameter neurons, making it a candidate receptor for transducing high-threshold heat responses in this class of cells. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. TRPV2 is one of the six members of the vanilloid-like TRP-channel family which is now known as TRPV family.
Conjugate
None
Applications
IHC
Host Species
Rabbit
Species Reactivity
Gorilla; Horse; Human; Monkey; Pig
Immunogen
A peptide located in the N-Terminal domain of TRPV2 (Human)
Purification
Immunoaffinity Chromatography
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS, 0.1% sodium azide
Storage
Short term: 4˚C. Long term: Store at -20˚C.
Clonality
Polyclonal
Alternative Names
GRC; growth factor regulated channel; Growth factor-regulated calcium channel; Osm-9-like TRP channel 2; OTRPC2; RP23-234K24.7; Stretch-activated channel 2B; Transient receptor potential cation channel subfamily V member 2; transient receptor potential cation channel, subfamily V, member 2; TrpV2; Vanilloid receptor-like protein 1; VRL-1
Entrez Gene ID
51393
- TRPV2 Polyclonal Antibody (NHP-AB481) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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