TRPV2 Polyclonal Antibody (NHP-AB481)

• This product is an antibody that was generated by immunizing rabbit against a peptide located in the N-Terminal domain of TRPV2 (Human). It is used only in in vitro assays.

Detailed Product Description

• Introduction: TRPV2 is a calcium-permeable, non-selective cation channel with an outward rectification, that seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. VRL-1 does not respond to capsaicin, acid, or moderate heat, but instead is activated by high temperatures, with a threshold of approximately 52 degrees C. Within sensory ganglia, TRPV2 is most prominently expressed by a subset of medium- to large-diameter neurons, making it a candidate receptor for transducing high-threshold heat responses in this class of cells. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. TRPV2 is one of the six members of the vanilloid-like TRP-channel family which is now known as TRPV family.
• Conjugate: None
• Applications: IHC

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Gorilla; Horse; Human; Monkey; Pig
• Immunogen: A peptide located in the N-Terminal domain of TRPV2 (Human)

Product Property

• Purification: Immunoaffinity Chromatography
• Format: Liquid
• Concentration: 1 mg/mL
• Buffer: PBS, 0.1% sodium azide
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: GRC; growth factor regulated channel; Growth factor-regulated calcium channel; Osm-9-like TRP channel 2; OTRPC2; RP23-234K24.7; Stretch-activated channel 2B; Transient receptor potential cation channel subfamily V member 2; transient receptor potential cation channel, subfamily V, member 2; TrpV2; Vanilloid receptor-like protein 1; VRL-1
• Entrez Gene ID: 51393