Pyruvate Kinase Polyclonal Antibody (NHP-AB441)

• This product is an antibody that was generated by immunizing rabbit against a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2). It is used only in in vitro assays.

Detailed Product Description

• Introduction: PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. PKM2 has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. PKM2 has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.
• Conjugate: None
• Applications: IF; IHC-P; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Monkey; Mouse; Rat
• Immunogen: A KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2)

Product Property

• Purification: Saturated Ammonium Sulfate (SAS) precipitation
• Format: Liquid
• Buffer: PBS with 0.09% (W/V) sodium azide
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: ATP:pyruvate 2-o-phosphotransferase; isozymes M1/M2; m2pk; Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle isozyme; Pyruvate kinase PKM; pyruvate kinase, muscle; tu
• Entrez Gene ID: 5315