Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsMonoclonal antibodies have gradually play a pivotal part in the field of biomedicine research. The technology of monoclonal antibody preparation is also constantly updated, from hybridoma preparation technology and phage antibody display technology to single B cell antibody preparation technology. Different technologies can meet the needs of different research and application needs. At present, monoclonal antibodies have been widely used in the development of diagnostic reagents in laboratory medicine, as an important ligand for affinity chromatography in protein purification, tumor-directed therapy radioimmunoimaging technology, and the treatment of a variety of diseases. There is no doubt that monoclonal antibodies will have a wider application space in the field of biomedicine. Based on our rich field experience and advanced antibody platform, Creative Biolabs provides comprehensive monoclonal antibody discovery services to support antibody study and application.
Phage antibody library technology is one of the most commonly used technologies for antibody development. It is a new antibody preparation technology developed from phage display technology. Rapid antibody screening can be achieved by phage antibody library construction. According to the origin of the gene, phage antibody libraries can be divided into two kinds with different properties. They are immune antibody libraries and non-immune antibody libraries, in which non-immune antibody libraries include semi-synthetic libraries and full synthetic libraries. Due to the selective pressure of immunization, the abundance of antibodies specific to the corresponding immunogen is much higher than that of other non-specific antibodies. In addition, a part of specific antibodies in the immune antibody library have gone through the affinity maturation process of the immune system, and antibodies with high affinity and specificity can be screened from this immune antibody library. Species-specific antibodies can be obtained by preparing antibody libraries from diverse species, which is of great significance for the study of the physiology and pathology of species. The preparation of immunized human antibody libraries based on this method can also obtain human antibodies more quickly and conveniently. This plays an important role in the development of monoclonal antibodies as drugs. In addition, phage antibody library technology can also improve the antibody, which can target a specific performance of the peptide without knowing the primary structure and obtain unknown sequences with the performance or improved by mutation library construction screening.
In the specific operation, whether the expected antibodies can be obtained from the antibody library is restricted by many factors, including the capacity of the antibody library, the diversity of the antibody library, the storage condition, the amplification condition, and the screening process of the antibody library. The correct selection and rational application of screening methods are of great significance. The screening strategy needs to be tailored to the nature of the antigen. Generally speaking, the acquisition of pure antigen is of great benefit to the screening of phage antibody libraries. Because it would make the process of screening much easier. However, when the pure antigen is difficult to obtain or the nature of the antigen is not known, practical screening methods need to be designed. However, this still cannot prevent the wide application prospect and great development potential of the phage antibody library. This technology has been used to produce small molecule antibodies, prepare humanized antibodies, and improve antibody performance. In the future, with the development of molecular biology and molecular immunology and the maturity of phage antibody library technology, it can also have more application scenarios, which will bring broader prospects for human new drug research and vaccine development.
Creative Biolabs has a wealth of knowledge and experience in monoclonal antibody discovery. We would be happy to share with you our knowledge and experience.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
