This product is an antibody conjugated with PE that is used only in in vitro assays.
Introduction:CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation.
Conjugate:PE
Antibody Isotype:IgG2b
Applications: Flow Cytometry; IHC-Fr
Host Species:Mouse
Species Reactivity: Feline; Hamster; Human; Monkey; Rabbit
Function:CD9 functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression plays a critical role in the suppression of cancer cell motility and metastasis. CD9 is also considered as metastasis suppressor in solid tumors.
CD9 Monoclonal Antibody (SP38), PE (NHP-AB194) Data Sheet: Detailed information. datasheet
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