Category:
Non-Human Primate (NHP) related Antibody Products
DDX3X Monoclonal Antibody (Y6R3) (NHP-AB211)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing mouse against recombinant protein of human DDX3X. It is used only in in vitro assays.
Introduction:
The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
Conjugate:
None
Antibody Isotype:
IgG
Applications:
ICC; IP; WB
Host Species:
Mouse
Species Reactivity:
Human; Monkey; Mouse; Rat
Immunogen:
Recombinant protein of human DDX3X
Purification:
Affinity purification
Format:
Liquid
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20⁰C. Avoid freeze-thaw cycles.
Target:
DDX3X
Clone:
Y6R3
Clonality:
Monoclonal
Alternative Names:
ATP-dependent RNA helicase DDX3X; CAP-Rf; DBX; DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked; DEAD box protein 3, X-chromosomal; DEAD box, X isoform; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3; DEAD/H box-3; Helicase-like protein 2; HLP2
Entrez Gene ID:
1654
- DDX3X Monoclonal Antibody (Y6R3) (NHP-AB211) Data Sheet: Detailed information. datasheet
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