Category:
Non-Human Primate (NHP) related Antibody Products
FOXO3 Polyclonal Antibody (NHP-AB346)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a portion of amino acids 600-673 of human FOXO3A. It is used only in in vitro assays.
Introduction:
The FOXO3 gene is known to promote longevity in animals and has now been discovered to encode a tumor suppressor. The new gene, which was inactivated in two-thirds of patients studied, presents a potent new target for breast cancer. The protein, named Forkhead box class O3 (FOXO3), is associated with better outcomes for breast cancer patients. Conversely, if FOXO3 was inactivated, patients had worse outcomes. FOXO3 is inactivated in many cancer patients by an enzyme called IKK, which is an oncoprotein.
Conjugate:
None
Applications:
IHC; WB
Host Species:
Rabbit
Species Reactivity:
Bovine; Chicken; Dog; Human; Monkey; Mouse; Rat; Xenopus
Immunogen:
A portion of amino acids 600-673 of human FOXO3A
Purification:
Immunoaffinity Chromatography
Format:
Liquid
Concentration:
0.5 mg/mL
Buffer:
PBS, 0.05% BSA, 0.05% sodium azide
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Alternative Names:
AF6q21 protein; AF6q21; DKFZp781A0677; FKHRL1; FKHRL1MGC31925; FKHRL1P2; forkhead box O3; forkhead box protein O3; forkhead homolog (rhabdomyosarcoma) like 1; Forkhead in rhabdomyosarcoma-like 1; FOXO2; FoxO3; FOXO3A; MGC12739
Entrez Gene ID:
2309
- FOXO3 Polyclonal Antibody (NHP-AB346) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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