FOXO3 Polyclonal Antibody (NHP-AB346)

• This product is an antibody that was generated by immunizing rabbit against a portion of amino acids 600-673 of human FOXO3A. It is used only in in vitro assays.

Detailed Product Description

• Introduction: The FOXO3 gene is known to promote longevity in animals and has now been discovered to encode a tumor suppressor. The new gene, which was inactivated in two-thirds of patients studied, presents a potent new target for breast cancer. The protein, named Forkhead box class O3 (FOXO3), is associated with better outcomes for breast cancer patients. Conversely, if FOXO3 was inactivated, patients had worse outcomes. FOXO3 is inactivated in many cancer patients by an enzyme called IKK, which is an oncoprotein.
• Conjugate: None
• Applications: IHC; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Bovine; Chicken; Dog; Human; Monkey; Mouse; Rat; Xenopus
• Immunogen: A portion of amino acids 600-673 of human FOXO3A

Product Property

• Purification: Immunoaffinity Chromatography
• Format: Liquid
• Concentration: 0.5 mg/mL
• Buffer: PBS, 0.05% BSA, 0.05% sodium azide
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: AF6q21 protein; AF6q21; DKFZp781A0677; FKHRL1; FKHRL1MGC31925; FKHRL1P2; forkhead box O3; forkhead box protein O3; forkhead homolog (rhabdomyosarcoma) like 1; Forkhead in rhabdomyosarcoma-like 1; FOXO2; FoxO3; FOXO3A; MGC12739
• Entrez Gene ID: 2309