HCAM (CD44) Monoclonal Antibody (SPM130) (NHP-AB133)

• This product is an antibody that was generated by immunizing mouse against stimulated human leukocytes. It is used only in in vitro assays.

Detailed Product Description

• Introduction: This antibody recognizes a cell surface glycoprotein named CD44 or HCAM on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The HCAM family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95kDa or hematopoietic variant. Higher molecular weight isoforms are described in epithelial cells, which are believed to function in intercellular adhesion and stromal binding. HCAM antibody immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
• Conjugate: None
• Antibody Isotype: IgG2aκ
• Applications: ELISA; Flow Cytometry; IF; IHC; WB

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Baboon; Human
• Immunogen: Stimulated human leukocytes

Product Property

• Purification: Protein G affinity chromatography
• Format: Liquid
• Concentration: 0.2 mg/mL
• Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
• Storage: Store at 4⁰C.

Target Information

• Target: HCAM
• Clone: SPM130
• Clonality: Monoclonal
• Alternative Names: CD44, CD44 molecule (Indian blood group), CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CD44 antigen, GP90 lymphocyte homing/adhesion receptor, Hermes antigen, cell surface glycoprotein CD44, chondroitin sulfate proteoglyc
• Entrez Gene ID: 960