Category:
Non-Human Primate (NHP) related Antibody Products
PRMT5 Polyclonal Antibody (NHP-AB430)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a synthetic peptide corresponding to a sequence within amino acids 40-140 of human PRMT5 (NP_006100.2). It is used only in in vitro assays.
Introduction:
PRMT5 is an arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. PRMT5 specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 and Sm D3; such methylation is required for the assembly and biogenesis of snRNP core particles.
Conjugate:
None
Antibody Isotype:
IgG
Applications:
IF; IHC; WB
Host Species:
Rabbit
Species Reactivity:
Human; Monkey; Mouse; Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40-140 of human PRMT5 (NP_006100.2)
Purification:
Affinity purification
Format:
Liquid
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20⁰C. Avoid freeze-thaw cycles.
Clonality:
Polyclonal
Alternative Names:
72 kDa ICln-binding protein; EC 2.1.1.125; Histone-arginine N-methyltransferase PRMT5; HMT1 hnRNP methyltransferase-like 5; Jak-binding protein 1; PRMT5; Protein arginine N-methyltransferase 5; Protein arginine N-methyltransferase 5, N-terminally processed; Shk1 kinase-binding protein 1 homolog; SKB1 homolog
Entrez Gene ID:
10419
- PRMT5 Polyclonal Antibody (NHP-AB430) Data Sheet: Detailed information. datasheet
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