This product is an antibody that was generated by immunizing rabbit against synthetic 17 amino acid peptide from C-Terminus of human SLC12A2 / NKCC1. It is used only in in vitro assays.
IntroductionSLC12A2 mediates sodium and chloride transport and reabsorption. SLC12A2 is a membrane protein and is important in maintaining proper ionic balance and cell volume. SLC12A2 is an electrically silent transporter system that mediates sodium and chloride reabsorption. Further, SLC12A2 plays a vital role in the regulation of ionic balance and cell volume and is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for SLC12A2.
ConjugateNone
Applications IHC
Host SpeciesRabbit
Species Reactivity Bat; Bovine; Dog; Gibbon; Hamster; Horse; Human; Monkey; Mouse; Pig; Rat
ImmunogenSynthetic 17 amino acid peptide from C-Terminus of human SLC12A2 / NKCC1
PurificationImmunoaffinity Chromatography
FormatLiquid
Concentration1 mg/mL
BufferPBS, 0.1% sodium azide
StorageShort term: 4˚C. Long term: Store at -20˚C.
ClonalityPolyclonal
Related DiseaseDiseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
Alternative NamesBasolateral Na-K-Cl symporter; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; protein phosphatase 1, regulatory subunit 141; sodium/potassium/chloride cotransporters; sodium/potassium/chloride transporters; solute carrier family 12 (sodium/potassium/chloride transporter), member 2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; Solute carrier family 12 member 2; solute carrier family 12, member 2
Entrez Gene ID6558
SLC12A2 Polyclonal Antibody (NHP-AB455) Data Sheet: Detailed information. datasheet
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