This product is an antibody that was generated by immunizing rabbit against synthetic 17 amino acid peptide from C-Terminus of human SLC12A2 / NKCC1. It is used only in in vitro assays.
Introduction:SLC12A2 mediates sodium and chloride transport and reabsorption. SLC12A2 is a membrane protein and is important in maintaining proper ionic balance and cell volume. SLC12A2 is an electrically silent transporter system that mediates sodium and chloride reabsorption. Further, SLC12A2 plays a vital role in the regulation of ionic balance and cell volume and is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for SLC12A2.
Conjugate:None
Applications: IHC
Host Species:Rabbit
Species Reactivity: Bat; Bovine; Dog; Gibbon; Hamster; Horse; Human; Monkey; Mouse; Pig; Rat
Immunogen:Synthetic 17 amino acid peptide from C-Terminus of human SLC12A2 / NKCC1
Purification:Immunoaffinity Chromatography
Format:Liquid
Concentration:1 mg/mL
Buffer:PBS, 0.1% sodium azide
Storage:Short term: 4˚C. Long term: Store at -20˚C.
Clonality:Polyclonal
Related Disease:Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
Alternative Names:Basolateral Na-K-Cl symporter; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; protein phosphatase 1, regulatory subunit 141; sodium/potassium/chloride cotransporters; sodium/potassium/chloride transporters; solute carrier family 12 (sodium/potassium/chloride transporter), member 2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; Solute carrier family 12 member 2; solute carrier family 12, member 2
Entrez Gene ID:6558
SLC12A2 Polyclonal Antibody (NHP-AB455) Data Sheet: Detailed information. datasheet
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