Category:
Non-Human Primate (NHP) related Antibody Products
LDHA Polyclonal Antibody (NHP-AB396)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
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This product is an antibody that was generated by immunizing rabbit against recombinant protein of human LDHA. It is used only in in vitro assays.
Introduction:
Lactate dehydrogenase (LDH) is the enzyme in the glycolytic pathway that converts pyruvate to lactate with concomitant interconversion of NADH and NAD+. In mammals, the enzyme is encoded by three genes: LDHA (M or muscle form), LDHB (H or heart form), and LDHC (X or testis form). The three human LDHs have 84-89% sequence similarities and 69-75% amino acid identities. There are five different LDH isoenzymes based on the proportion of M and H chains existing in the LDH tetrameric structure. The LDHA is hypoxia inducible and its expression is directly controlled by the transcriptional activity of the hypoxia inducible factor 1a (HIF1a). LDHB is also known to be upregulated in many cancers. Mutations in the LDHA gene can lead to Glycogen storage disease 11 (GSD11).
Conjugate:
None
Antibody Isotype:
IgG
Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human; Monkey; Mouse; Rat
Immunogen:
Recombinant protein of human LDHA
Purification:
Affinity purification
Format:
Liquid
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at -20⁰C. Avoid freeze-thaw cycles.
Clonality:
Polyclonal
Alternative Names:
Cell proliferation-inducing gene 19 protein; epididymis secretory sperm binding protein Li 133P; L-lactate dehydrogenase A chain; L-lactate dehydrogenase C chain; Lactate Dehydrogenase; lactate dehydrogenase 1, A chain; lactate dehydrogenase 3, C chain, sperm specific; lactate dehydrogenase A-like; lactate dehydrogenase A4; lactate dehydrogenase C variant 3; lactate dehydrogenase M; lactate dehydrogenase-A; Lactic Dehydrogenase; LDH muscle subunit; LDH testis subunit; LDH-A; LDH-C; LDH-M; LDH-X; M-LDH; OTTHUMP00000165206; proliferation-inducing gene 19; Renal carcinoma antigen NY-REN-59
Entrez Gene ID:
3939
- LDHA Polyclonal Antibody (NHP-AB396) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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