Category:
Non-Human Primate (NHP) related Antibody Products
MARCH4 Polyclonal Antibody (NHP-AB274)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a portion of amino acids 300-350 of human RNF174. It is used only in in vitro assays.
Introduction:
MARCH4 is a multi-pass membrane protein mainly found in the membrane of Golgi apparatus. It is a complex enzyme with a RING-CH-type zinc finger. It acts as a ubiquitin-protein ligase mainly involved in third step of ubiquitin conjugation. The RINGv-type zinc finger domain is required for E3 ligase activity in which the E3 ubiquitin-protein ligase mediates ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. It is mainly expressed in brain and placenta.
Conjugate:
None
Applications:
IHC; WB
Host Species:
Rabbit
Species Reactivity:
Chicken; Chimpanzee; Dog; Horse; Human; Mouse; Opossum; Rat; Zebrafish
Immunogen:
A portion of amino acids 300-350 of human RNF174
Purification:
Immunoaffinity Chromatography
Format:
Liquid
Concentration:
0.5 mg/mL
Buffer:
PBS, 0.2% gelatin, 0.05% sodium azide.
Storage:
Short term: 4˚C. Long term: Store at -20˚C. Avoid freeze-thaw cycles.
Clonality:
Polyclonal
Alternative Names:
E3 ubiquitin-protein ligase MARCH4; MARCH-IV; membrane associated ring finger 4; membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase; Membrane-associated RING finger protein 4; Membrane-associated RING-CH protein IV; RING finger protein 174; RING-type E3 ubiquitin transferase MARCH4
Entrez Gene ID:
57574
- MARCH4 Polyclonal Antibody (NHP-AB274) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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