Category:
Non-Human Primate (NHP) related Antibody Products
MRGPRX2 Polyclonal Antibody (NHP-AB277)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a peptide located in the C-Terminal cytoplasmic domain of MRGPRX2 (Human). It is used only in in vitro assays.
Introduction:
MRGPRX2 probably involved in the function of nociceptive neurons. It may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion.
Conjugate:
None
Applications:
ELISA; IHC
Host Species:
Rabbit
Species Reactivity:
Chimpanzee; Gorilla; Human
Immunogen:
A peptide located in the C-Terminal cytoplasmic domain of MRGPRX2 (Human)
Purification:
Immunoaffinity Chromatography
Format:
Liquid
Concentration:
1 mg/mL
Buffer:
PBS, 0.1% sodium azide.
Storage:
Short term: 4˚C. Long term: Store at -20˚C. Avoid freeze-thaw cycles.
Clonality:
Polyclonal
Alternative Names:
G protein-coupled receptor MRGX2; Mas-related G protein-coupled receptor G3; Mas-related G-protein coupled receptor member B10; Mas-related G-protein coupled receptor member X2; MAS-related GPR, member B10; MAS-related GPR, member X2
Entrez Gene ID:
117194
- MRGPRX2 Polyclonal Antibody (NHP-AB277) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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