HDAC2 Polyclonal Antibody (NHP-AB371)

• This product is an antibody that was generated by immunizing rabbit against a sequence within amino acids 390 to the C-terminus of human HDAC2 (NP_001518.3). It is used only in in vitro assays.

Detailed Product Description

• Introduction: HDAC2 belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: IF; IHC; IP; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Monkey; Mouse; Rat
• Immunogen: A sequence within amino acids 390 to the C-terminus of human HDAC2 (NP_001518.3)

Product Property

• Purification: Affinity purification
• Format: Liquid
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Storage: Store at -20⁰C. Avoid freeze-thaw cycles.

Target Information

• Clonality: Polyclonal
• Alternative Names: HD2; hdac 2; hdac-2; Histone deacetylase 2; transcriptional regulator homolog RPD3; YY1 transcription factor-binding protein; YY1-associated factor 1
• Entrez Gene ID: 3066