OLFM4 Polyclonal Antibody (NHP-AB412)

• This product is an antibody that was generated by immunizing rabbit against N-Terminal domain of human. It is used only in in vitro assays.

Detailed Product Description

• Introduction: OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.
• Conjugate: None
• Applications: IHC

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Chimpanzee; Gibbon; Gorilla; Human; Monkey
• Immunogen: N-Terminal domain of human

Product Property

• Purification: Immunoaffinity Chromatography
• Format: Liquid
• Concentration: 1 mg/mL
• Buffer: PBS, 0.1% sodium azide
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: Antiapoptotic protein GW112; G-CSF-stimulated clone 1 protein; hGC-1; hOLfD; Olfactomedin-4; OLM4
• Entrez Gene ID: 10562