Category:
Non-Human Primate (NHP) related Antibody Products
PDGFRA Polyclonal Antibody (NHP-AB419)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
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This product is an antibody that was generated by immunizing rabbit against synthetic peptide corresponding to amino acids 1035-1053 of human PDGF (KLH-conjugated). It is used only in in vitro assays.
Introduction:
PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Conjugate:
None
Antibody Isotype:
IgG
Applications:
IHC; IP; WB
Host Species:
Rabbit
Species Reactivity:
Dog; Gorilla; Hamster; Horse; Human; Monkey; Mouse; Pig; Rabbit; Rat; Xenopus
Immunogen:
Synthetic peptide corresponding to amino acids 1035-1053 of human PDGF (KLH-conjugated)
Purification:
Immunoaffinity Chromatography
Format:
Liquid
Buffer:
0.2 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Alternative Names:
Alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a; MGC74795; OTTHUMP00000218656; PDGF A-chain; PDGF alpha chain; PDGF Receptor alpha; PDGF-R-alpha; pdgfr-a; PDGFR-alpha; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor alpha
Entrez Gene ID:
5156
- PDGFRA Polyclonal Antibody (NHP-AB419) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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