What are the major concerns of this antibody regarding specificity and cross-reactivity in TAOK1?

The TAOK1 polyclonal antibody should interact specifically with the TAOK1 target and should not cross-react with other proteins, providing the experimenters the real and confident results of the experiment.

Category: Non-Human Primate (NHP) related Antibody Products

TAOK1 Polyclonal Antibody (NHP-AB471)

Product Overview Detailed Product Description Technical Specifications Product Property Target Information Downloadable Resources FAQs Customer Reviews

This product is an antibody that was generated by immunizing rabbit against synthetic 17 amino acid peptide from human TAOK1. It is used only in in vitro assays.

Introduction: TAOK1 is a serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response, and regulations of cytoskeleton stability. It phosphorylates MAP2K3, MAP2K6, and MARK2. TAOK1 acts as an activator of the p38/MAPK cascade by mediating phosphorylation and subsequent activation of the upsteam MAP2K3 and MAP2K6 kinases. It is involved in G-protein couples receptor signaling to p38/MAPK14. In response to DNA damage, TAOK1, is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade by phosphorylaton of MAP2K3 and MAP2K6. In addition, it acts as a regulator of cytoskeleton stability and a regulator of apoptosis.

Conjugate: None

Applications: ELISA; IHC

Host Species: Rabbit

Species Reactivity: Bat; Bovine; Chicken; Dog; Gibbon; Gorilla; Hamster; Horse; Human; Monkey; Mouse; Pig; Rabbit; Rat; Xenopus

Immunogen: Synthetic 17 amino acid peptide from human TAOK1

Purification: Immunoaffinity Chromatography

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 0.1% sodium azide

Storage: Short term: 4˚C. Long term: Store at -20˚C.

Clonality: Polyclonal

Alternative Names: FLJ14314; h hTAOK1; H KIAA1361; hKFC-B; Kinase from chicken homolog B; MARK Kinase; MARKK; microtubule affinity regulating kinase kinase; prostate-derived STE20-like kinase 2; Prostate-derived sterile 20-like kinase 2; PSK-2; serine/threonine protein kinase TAO1 homolog; Serine/threonine-protein kinase TAO1; STE20-like kinase PSK2; tao; TAOK1; thousand and one amino acid protein 1; Thousand and one amino acid protein kinase 1

Entrez Gene ID: 57551

TAOK1 Polyclonal Antibody (NHP-AB471) Data Sheet: Detailed information. datasheet

Q 1: What are the major concerns of this antibody regarding specificity and cross-reactivity in TAOK1?
A: The TAOK1 polyclonal antibody should interact specifically with the TAOK1 target and should not cross-react with other proteins, providing the experimenters the real and confident results of the experiment.

High Specificity
The TAOK1 Polyclonal Antibody from Creative Biolabs contributed to our recent research on a signaling pathway. Its specificity and performance were above excellent and definitely contributed to findings of value.
Reliable and High Quality
We are happy with the quality and reliability of TAOK1 Polyclonal Antibody for our experiment.

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Fig.1 Obesity can be counteracted by gene regulation.

Your research is unique, and we understand that standard products may not always fit. Our team of experts specializes in custom NHP sample collections. We can design a tailored protocol to meet your specific research requirements, including samples with unique anticoagulant types, customized volumes, or from specific disease models.