Category:
Non-Human Primate (NHP) related Antibody Products
TLX1 Polyclonal Antibody (NHP-AB475)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
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This product is an antibody that was generated by immunizing rabbit against amino acids 300 - 330 of TLX1 (Human). It is used only in in vitro assays.
Introduction:
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.
Conjugate:
None
Antibody Isotype:
IgG
Applications:
IHC; WB
Host Species:
Rabbit
Species Reactivity:
Chicken; Dog; Gorilla; Hamster; Horse; Human; Monkey; Mouse; Rabbit; Rat
Immunogen:
Amino acids 300 - 330 of TLX1 (Human)
Purification:
Protein G Column
Format:
Liquid
Concentration:
0.5 mg/mL
Buffer:
PBS, 0.2% gelatin, 0.05% sodium azide
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Alternative Names:
homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to Drosophila Notch); Homeobox protein Hox-11; homeobox TLX-1; MGC163402; Proto-oncogene TCL-3; T-cell leukemia homeobox protein 1; T-cell leukemia, homeobox 1; T-cell leukemia/lymphoma protein 3
Entrez Gene ID:
3195
- TLX1 Polyclonal Antibody (NHP-AB475) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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