Category:
Non-Human Primate (NHP) related Antibody Products
TRBP2 Polyclonal Antibody (NHP-AB501)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a recombinant protein fragment within the C-terminal region of TRBP2. It is used only in in vitro assays.
Introduction:
TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.
Conjugate:
None
Antibody Isotype:
IgG
Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human; Mouse; Monkey
Immunogen:
A recombinant protein fragment within the C-terminal region of TRBP2
Purification:
Protein A Affinity Chromatography
Format:
Liquid
Concentration:
0.5 mg/mL
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Storage:
Store at -20⁰C. Avoid freeze-thaw cycles.
Clonality:
Polyclonal
Alternative Names:
LOQS; TARBP2; TRBP; TRBP1; TRBP2
Entrez Gene ID:
6895
- TRBP2 Polyclonal Antibody (NHP-AB501) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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