TRBP2 Polyclonal Antibody (NHP-AB501)

• This product is an antibody that was generated by immunizing rabbit against a recombinant protein fragment within the C-terminal region of TRBP2. It is used only in in vitro assays.

Detailed Product Description

• Introduction: TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Human; Mouse; Monkey
• Immunogen: A recombinant protein fragment within the C-terminal region of TRBP2

Product Property

• Purification: Protein A Affinity Chromatography
• Format: Liquid
• Concentration: 0.5 mg/mL
• Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
• Storage: Store at -20⁰C. Avoid freez-thaw cycles.

Target Information

• Clonality: Polyclonal
• Alternative Names: LOQS; TARBP2; TRBP; TRBP1; TRBP2
• Entrez Gene ID: 6895