Category:
Non-Human Primate (NHP) related Antibody Products
TRBP2 Polyclonal Antibody (NHP-AB501)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a recombinant protein fragment within the C-terminal region of TRBP2. It is used only in in vitro assays.
Introduction
TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.
Conjugate
None
Antibody Isotype
IgG
Applications
WB
Host Species
Rabbit
Species Reactivity
Human; Mouse; Monkey
Immunogen
A recombinant protein fragment within the C-terminal region of TRBP2
Purification
Protein A Affinity Chromatography
Format
Liquid
Concentration
0.5 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Storage
Store at -20⁰C. Avoid freeze-thaw cycles.
Clonality
Polyclonal
Alternative Names
LOQS; TARBP2; TRBP; TRBP1; TRBP2
Entrez Gene ID
6895
- TRBP2 Polyclonal Antibody (NHP-AB501) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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