mb-vc-MGBA (CAT#: ADC-S-053)
Linker-Toxin SET, this set is made by duocarmycin derivative, MED-A conjugated to the lysosomally cleavable dipeptide, valine-citrulline (vc) linker. MED-A is a carbamate prodrug that is activated by carboxylesterase to its active form, MED-B, to exert its DNA alkylation activity.
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- Description
- Linker-Toxin SET, this set is made by duocarmycin derivative, MED-A conjugated to the lysosomally cleavable dipeptide, valine-citrulline (vc) linker. MED-A is a carbamate prodrug that is activated by carboxylesterase to its active form, MED-B, to exert its DNA alkylation activity.
- Purity
- 95%
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