Caveolin-3 Polyclonal Antibody (NHP-AB320)

• This product is an antibody that was generated by immunizing rabbit against amino acids 19 - 41 of Caveolin - 3 (Human). It is used only in in vitro assays.

Detailed Product Description

• Introduction: Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-3 may also regulate voltage-gated potassium channels. It also plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Caveolin-3 also mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae. Mutations in the gene can result in HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.
• Conjugate: None
• Antibody Isotype: IgG
• Applications: IHC; WB

Technical Specifications

• Host Species: Rabbit
• Species Reactivity: Bat; Bovine; Dog; Gibbon; Gorilla; Hamster; Horse; Human; Monkey; Mouse; Pig; Rabbit; Rat
• Immunogen: Amino acids 19 - 41 of Caveolin - 3 (Human)

Product Property

• Purification: Antiserum
• Format: Liquid
• Buffer: Antiserum, 100 ul Reconstitute with 100 ul of distilled water
• Storage: Short term: 4˚C. Long term: Store at -20˚C.

Target Information

• Clonality: Polyclonal
• Alternative Names: CAV; Caveolin-3; M-caveolin; MGC126100; MGC126101; MGC126129; structural protein
• Entrez Gene ID: 859