CD11b Monoclonal Antibody (JES15A), Biotin (NHP-AB110)

• This product is an antibody conjugated with Biotin that was generated by immunizing mouse against rheumatoid synovial cells and human monocytes. It is used only in in vitro assays.

Detailed Product Description

• Introduction: CD11b is the 165 kDa alphaM chain which combines with the CD18 beta2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).
• Conjugate: Biotin
• Antibody Isotype: IgG1
• Applications: Drug Delivery; Flow Cytometry; ICC; IP; WB

Technical Specifications

• Host Species: Mouse
• Species Reactivity: Baboon; Chimpanzee; Human; Porcine
• Immunogen: Rheumatoid synovial cells and human monocytes

Product Property

• Format: Liquid
• Buffer: Supplied in PBS/NaN3
• Storage: Store at 4⁰C.

Target Information

• Target: CD11b
• Clone: JES15A
• Clonality: Monoclonal
• Alternative Names: Integrin alphaM, Mac-1alpha, Mac-1, Mo1, CR3, C3biR
• Entrez Gene ID: 3684