Category:
Non-Human Primate (NHP) related Antibody Products
GPR68 Polyclonal Antibody (NHP-AB363)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against a peptide located in the 1st extracellular domain of GPR68 (Human). It is used only in in vitro assays.
Introduction:
GPR68, also known as OGR1 - ovarian cancer G-protein coupled receptor 1, is a proton-sensing receptor involved in pH homeostasis. It represents an osteoblastic pH sensor regulating the cell-mediated response to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulate inositol phosphate (IP) production or CA2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also found to serve as a tumor suppressor in prostate cancer. Mutations to the gene result in amelogenesis imperfecta, hypomaturation type 2A6.
Conjugate:
None
Applications:
ELISA; IHC
Host Species:
Rabbit
Species Reactivity:
Gibbon; Gorilla; Human; Monkey; Rat
Immunogen:
A peptide located in the 1st extracellular domain of GPR68 (Human)
Purification:
Immunoaffinity Chromatography
Format:
Liquid
Concentration:
1 mg/mL
Buffer:
PBS, 0.1% sodium azide.
Storage:
Short term: 4˚C. Long term: Store at -20˚C.
Clonality:
Polyclonal
Alternative Names:
Brgr1; Brgrb; G-protein coupled receptor 68; GPR12A; OGR-1; ovarian cancer G protein-coupled receptor, 1; Ovarian cancer G-protein coupled receptor 1; Sphingosylphosphorylcholine receptor
Entrez Gene ID:
8111
- GPR68 Polyclonal Antibody (NHP-AB363) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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