Category:
Non-Human Primate (NHP) related Antibody Products
PHB Polyclonal Antibody (NHP-AB423)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing rabbit against recombinant fusion protein containing a sequence corresponding to amino acids 73-272 of human PHB (NP_002625.1). It is used only in in vitro assays.
Introduction:
Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Conjugate:
None
Antibody Isotype:
IgG
Applications:
IF; WB
Host Species:
Rabbit
Species Reactivity:
Human; Monkey; Mouse; Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 73-272 of human PHB (NP_002625.1)
Purification:
Affinity purification
Format:
Liquid
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20⁰C. Avoid freeze-thaw cycles.
Clonality:
Polyclonal
Alternative Names:
B-cell receptor-associated protein 32; BAP 32; epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; OTTHUMP00000165765; OTTHUMP00000165766; OTTHUMP00000220103; OTTHUMP00000220170; OTTHUMP00000220171; Prohibitin
Entrez Gene ID:
5245
- PHB Polyclonal Antibody (NHP-AB423) Data Sheet: Detailed information. datasheet
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For research use only. Not intended for any clinical use.
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