Category:
Non-Human Primate (NHP) related Antibody Products
Semaphorin-4D Monoclonal Antibody (V23U9) (NHP-AB139)
Product Overview
Detailed Product Description
Technical Specifications
Product Property
Target Information
Downloadable Resources
Customer Reviews
This product is an antibody that was generated by immunizing mouse against PHA stimulated human peripheral blood lymphocytes. It is used only in in vitro assays.
Introduction:
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
Conjugate:
None
Antibody Isotype:
IgMκ
Applications:
Flow Cytometry; IF
Host Species:
Mouse
Species Reactivity:
Baboon; Human
Immunogen:
PHA stimulated human peripheral blood lymphocytes
Format:
Liquid
Concentration:
0.2 mg/mL
Buffer:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Storage:
Store at 4⁰C.
Target:
Semaphorin-4D
Clone:
V23U9
Clonality:
Monoclonal
Alternative Names:
A8; BB18; CD100; GR3; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D; Semaphorin-4D
Entrez Gene ID:
10507
- Semaphorin-4D Monoclonal Antibody (V23U9) (NHP-AB139) Data Sheet: Detailed information. datasheet
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