Human Basal ganglia (BG) Autoantibody (IgG) ELISA kit (CAT#: NAK-003)

This product is a qualitative ELISA kit for the determination of Basal ganglia (BG) Autoantibody in human Plasma or Serum.

Specifications
SensitivityQualitative
Assay TypeELISA
Pack size1×96 wells
Species ReactivityHuman
Antibody TypeIgG
ContentsCoated assay plate 1(96 wells)
Negative Control
Positive Control
HRP-conjugate(100 x concentrate)
HRP-conjugate Diluent
Sample Diluent
Wash Buffer (25 x concentrate)
TMB Substrate
Stop Solution
Instruction manual
Sample RequirementPlasma, Serum: 50-100ul
StorageShort term: 4°C, Long term: See manual.
Target Information
TargetBasal ganglia (BG) autoantibody
IntroductionAnti-basal ganglia antibodies (ABGA) have been found with extrapyramidal movement disorders of the basal ganglia and deep grey matter with post-rheumatic fever chorea (90% sensitivity) and tics being the common manifestations, although dystonia and myoclonus have also been reported in rare incidences.
  • Q&A
  • Customer Reviews
  • Downloadable Resources
  • Published Data

Q: What is the Human Basal Ganglia (BG) Autoantibody IgG ELISA Kit used for?
A: The Human Basal Ganglia (BG) Autoantibody IgG ELISA Kit (CAT#: NAK-003) is designed for the qualitative determination of basal ganglia autoantibodies in human plasma or serum. It's a specialized assay kit aimed at detecting the presence of autoantibodies targeting the basal ganglia, which are associated with extrapyramidal movement disorders and other neurological conditions.

Q: What are the key components included in the Human Basal Ganglia Autoantibody ELISA Kit?
A: This ELISA kit comes equipped with all necessary components for conducting a comprehensive assay. The kit includes a coated assay plate with 96 wells, negative and positive controls, HRP-conjugate (100x concentrate), HRP-conjugate diluent, sample diluent, wash buffer (25x concentrate), TMB substrate, stop solution, and an instruction manual, ensuring researchers have everything needed for the assay.

Q: What type of samples are required for the Human Basal Ganglia Autoantibody ELISA Kit, and in what volume?
A: The kit is designed for use with human plasma or serum samples. For conducting the assay, a sample volume of 50-100µl is recommended. This allows for accurate qualitative determination of basal ganglia autoantibodies in the provided biological material.

Q: How should the Human Basal Ganglia Autoantibody ELISA Kit be stored, and what are its storage conditions?
A: For short-term storage, the components of the ELISA kit should be kept at 4°C. For long-term storage details, users are advised to refer to the instruction manual provided with the kit. Following the recommended storage conditions is crucial to maintain the kit's integrity and ensure accurate results.

Precision and clarity
The Human Basal ganglia (BG) Autoantibody (IgG) ELISA kit is a comprehensive kit that offered precise and reliable results. The instructions were clear and easy to follow. The sensitivity of the kit was impressive making it a highly qualitative assay.


07/09/2022

Complete and user-friendly
I recently used the Human BG autoantibody ELISA kit for my research. The kit had all the required components, starting from the ELISA coated plate to the stop solution. The storage condition also helped in maintaining the kit active for a long time. Plus, the instruction manual was very clear and easy to comprehend, ensuring a smooth workflow. I would certainly recommend this product.


08/14/2023

Exceptional specificity
In my experience with various ELISA kits, the Human Basal Ganglia (BG) Autoantibody IgG ELISA Kit stands out for its exceptional specificity and reliability. The kit's capacity to qualitatively determine BG autoantibodies in plasma or serum has been critical for our research into extrapyramidal movement disorders. The detailed target information provided has also been beneficial for our team's understanding of ABGA's role in disease mechanisms. Highly recommended for its precision and ease of use.


10/02/2023

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Title: Anti–basal Ganglia Antibodies in Acute and Persistent Sydenham’s Chorea

Journal: Neurology

Authors: A. J. Church, F. Cardoso, R. C. Dale, A. J. Lees, E. J. Thompson, G. Giovannoni

Abstract
For Research Use Only | Not For Clinical Use

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