NAA Associated Rheumatic Diseases
With years of experience in natural autoantibodies (NAA) detection and analysis for various autoantigens in systemic autoimmune diseases (such as rheumatic diseases), Creative Biolabs is confident in providing a series of reliable NAA services based on our innovate and advanced techniques such as antigen microarrays, western blotting, and ELISA.
What Are Rheumatic Diseases?
Rheumatic diseases are a group of systemic autoimmune diseases. They occur when the body’s immune system wrong and mistakenly attacks own organs, tissues, and joints. The resulting inflammatory process results in thickening, swelling, and pain in the joints. Because inflammatory arthritis is systemic, that means it not only affects joints but also other systems of the body such as the heart, lungs, eyes, and brain. Currently, there are over 200 different types of rheumatic diseases. The most common are:
- Osteoarthritis
- Rheumatoid arthritis (RA)
- Fibromyalgia
- Ankylosing spondylitis
- Psoriatic arthritis
- Gout
- Infectious arthritis
- Juvenile idiopathic arthritis
- Polymyalgia rheumatic
- Scleroderma
Symptoms of Rheumatic Diseases
An individual rheumatic disease has its unique symptom. However, it shares some common symptoms between rheumatic diseases, mainly include:
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Joint pain
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Loss of motion in a joint or joints
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Inflammation - swelling, redness, and warmth in a joint or affected area
What Is the Cause of Rheumatic Diseases?
Most rheumatic diseases happen when the body’s immune system can’t tell the differences between self and non-self and starts to attack self-tissues or self-organs. The cause of rheumatic diseases is not clear. However, it is reported that rheumatic diseases are likely caused by a combination of genes and environmental factors.
- Genetics - Variants in certain genes may increase the susceptibility of developing rheumatic diseases.
- Environmental factors - Such as bacteria or virus infection, cigarette smoke, pollution, or something that causes an infection.
- Hormonal - Female hormone estrogen may play a role in the pathological process of rheumatic diseases.
How to Diagnose Rheumatic Diseases?
Rheumatic diseases diagnosis is based on a combination of imaging tests and blood tests. In blood tests, NAA tests are very important because most rheumatic diseases are caused by NAA attacking their own tissues. NAA test will help doctors to assess the condition of rheumatic diseases. The following is several key NAA markers applied in rheumatic diseases.
| Natural Autoantibodies Targets in Rheumatic Diseases | ||
| Anti-Rheumatoid Factor (RF) | Anti-Neutrophil Cytoplasmic Antibodies (ANCA) | Anti-Nuclear Antibody (ANA) |
| Anti-Cyclic Citrullinated Peptides (ACPA) | Anti-dsDNA | |
Creative Biolabs is committed to offering the best and comprehensive NAA services based on our advanced technology and scientific team. Besides, we also provide custom NAA test service according to customers’ special purpose of their project. If you are interested in NAA tests, please feel free to contact us for more details or a detailed quote.
Choosing natural autoantibody (NAA) microarray to profile autoantibody repertoire and reveal novel disease's marker.
- NAA Services for Anti-Neutrophil Cytoplasmic Antibodies (ANCA)
- NAA Services for Anti-Cyclic Citrullinated Peptides Antibodies (ACPA)
Related Services:
- NAA Associated Systemic Lupus Erythematosus (SLE)
- NAA Associated Celiac Disease
- NAA Associated Sjögren's Syndrome (SS)
- NAA Associated Myasthenia Gravis (MG)
- NAA and Sjogren's Syndrome