Natural Autoantibody Application in Vaccine Development
Vaccine is a special component that is used to stimulate immunity and protect the human body from infections and diseases. Natural autoantibodies (NAA) play a significant role in vaccine development, which may serve as an antibody or autoantigen. Creative Biolabs possesses a strong and great vaccine platform as well as years of experience in NAA and related diseases researches. We can provide the best and professional NAA vaccine development solutions and services to our customers throughout the world.
Background of Vaccine
A vaccine is a biological preparation that provides active acquired immunity to a certain disease. Most of the current vaccines are made from a weakened or killed form of the microorganisms, their toxins, or surface proteins. The vaccine is firstly derived from 'Variolae vaccine' by Edward Jenner in 1798.
The vaccine is a kind of immunological agent through artificial toxicity-attenuation, inactivation or transgenosis of pathogenic microorganisms or their metabolites, which retained the immune stimulation of microorganisms. Immune system immediately produces some protective substances like antibodies, hormones, active physiological substances, etc. when animals or humans exposed to these harmless pathogens. If exposed to these pathogens again, the immune system would produce more protective substances to prevent the damage caused by the pathogens based on previously immune memories.
Fig.1 Schematic representation of the mechanisms of vaccination and immune defense against viruses. (Sokolova, 2015)
NAA Application in Vaccine
Numerous scientific researches and clinical tests make a great contribution to the development of a vaccine, which not only applied for traditionally immune-related diseases but also for other novel diseases such as cancers. As an essential part of the immune system, NAA is able to help identify novel and effective disease targets, which may act as potential candidates for vaccine development.
As a leader in the biology industry, Creative Biolabs has successfully established an improved vaccine research platform with decades of years’ experience, powerful technologies, and professional scientists. Simultaneously, we also have been committed to the natural autoantibodies and related applications for many years. We have absolute advantages in NAA application for vaccine development based on our abundant experience and perfect services. If you are interested in the natural autoantibodies and related applications research or you have any question, please do not hesitate to contact us for more detailed information. Our scientists are pleased to tailor the best-fit proposal to meet your specific demands.
Reference:
- Sokolova, V.; et al. The potential of nanoparticles for the immunization against viral infections. Journal of Materials Chemistry B. 2015, 3: 4767-4779.