- Home
- Products
- Customized FluoroAb™
- APP
- Anti-APP MAb (Clone 21)-iFluor® 430 Succinimidyl Ester
Anti-APP MAb (Clone 21)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4163)
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1; Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Human Anti-APP IgG1-kappa (Clone 21)
- Species Reactivity
- Human
- Name
- iFluor® 430 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 433/498
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS4163. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-714 | Anti-APP (Ponezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-715 | Anti-APP (Ponezumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-706 | Anti-APP (Bapineuzumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-710 | Anti-APP (Ponezumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-705 | Anti-APP (Bapineuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-EpCAM MAb (Clone 5)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11746)
- Anti-PVRL4 MAb (Clone 1)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3869)
- Anti-ITGAL MAb (Clone 1)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14490)
- Anti-MUC1 MAb (Clone 1)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS15658)
- Anti-CD74 MAb (Clone 3)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS4859)
- Anti-APP MAb (Clone 12)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS1661)
- Anti-CDH1 MAb (Clone 1)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS11155)
- Anti-TNFRSF10B MAb (Clone 3)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8399)
- Anti-MUC5AC MAb (Clone 1)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5288)
- Anti-TNF MAb (Clone 6)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8397)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
