- Home
- Products
- Customized FluoroAb™
- APP
- Anti-APP MAb (Clone 4)-iFluor® 514 Succinimidyl Ester
Anti-APP MAb (Clone 4)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS10921)
This product is comprised of an Humanized Anti-APP IgG1 antibody (Clone 4) labeled with iFluor® 514 Succinimidyl Ester. iFluor® 514 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- APP
- Alternative Names
- APP; amyloid beta (A4) precursor protein; AD1; Alzheimer disease; amyloid beta A4 protein; peptidase nexin II; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloid peptide; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma;
- Overview
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Overview
- Humanized Anti-APP IgG1 antibody (Clone 4)
- Species Reactivity
- Human
- Name
- iFluor® 514 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 511/527
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-MET MAb (Clone 10)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16783)
- Anti-TNFRSF10B MAb (Clone 8)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8665)
- Anti-CD6 MAb (Clone 9)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15052)
- Anti-MS4A1 MAb (Clone 12)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14505)
- Anti-CR2 MAb (Clone 2)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5172)
- Anti-MST1R MAb (Clone 5)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8712)
- Anti-CD40 MAb (Clone 6)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4252)
- Anti-TNC MAb (Clone 2)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8391)
- Anti-MUC16 MAb (Clone 6)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS468)
- Anti-FUT3 MAb (Clone 2)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14277)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS10921. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-712 | Anti-APP (Ponezumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-709 | Anti-APP (Bapineuzumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-703 | Anti-APP (Solanezumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-702 | Anti-APP (Solanezumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-710 | Anti-APP (Ponezumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
