- Home
- Products
- Customized FluoroAb™
- Anti-C-kit MAb (Clone 8)-iFluor® 405 Succinimidyl Ester
Anti-C-kit MAb (Clone 8)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS1812)
This product is comprised of an Anti-C-kit antibody (Clone 8) labeled with iFluor® 405 Succinimidyl Ester. iFluor® 405 Succinimidyl Ester is a Blue-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- KIT
- Alternative Names
- KIT; C-Kit; CD117; PBT; SCFR; KIT proto-oncogene receptor tyrosine kinase; MASTC; KIT proto-oncogene; receptor tyrosine kinase
- Overview
- The proto-oncogene c-KIT is a gene encoding a receptor tyrosine kinase protein called tyrosine protein kinase KIT, CD117 (differentiation cluster 117) or mast/stem cell growth factor receptor (SCFR).
KIT is a cytokine receptor expressed on the surface of hematopoietic stem cells and other cell types. This change in receptor form may be associated with certain types of cancer. KIT is a type III receptor tyrosine kinase that binds to stem cell factor (a substance that causes the growth of certain types of cells), also known as "steel factor" or "c-kit ligand" . When the receptor binds to stem cell factor (SCF), it forms a dimer, which activates its inherent tyrosine kinase activity, which in turn phosphorylates and activates signal transduction molecules that propagate signals in the cell. After activation, the receptor is ubiquitinated to label it for transport to the lysosome and is eventually destroyed. The signal sent by KIT plays a role in cell survival, proliferation and differentiation. For example, melanocyte survival requires KIT signaling, which is also involved in hematopoiesis and gametogenesis.
- Overview
- Anti-C-kit antibody (Clone 8)
- Species Reactivity
- Human
- Name
- iFluor® 405 Succinimidyl Ester
- Color
- Blue
- Excitation⁄Emission (nm)
- 403/427
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-GD3 MAb (Clone 3)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16959)
- Anti-PDCD1 MAb (Clone 28)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15316)
- Anti-TNFRSF8 MAb (Clone 6)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS4977)
- Anti-HAVCR1 MAb (Clone 1)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS3522)
- Anti-MET MAb (Clone 11)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS12170)
- Anti-MYL MAb (Clone 10)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS6225)
- Anti-TPBG MAb (Clone 8)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS1875)
- Anti-CEACAM5 MAb (Clone 1)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS10958)
- Anti-APP MAb (Clone 18)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7236)
- Namilumab-iFluor 647 (CAT#: ADC-FL-999)
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS1812. Click the button above to contact us or submit your feedback about this product.
Quick Links
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
