- Home
- Products
- Customized FluoroAb™
- C5
- Anti-C5 MAb (Clone 1)-iFluor® 460 Succinimidyl Ester
Anti-C5 MAb (Clone 1)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS8272)
- TARGET
- ANTIBODY
- DYE
- Name
- C5
- Alternative Names
- C5; complement component 5; complement C5; CPAMD4; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; FLJ17816; FLJ17822; MGC142298;
- Overview
- This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the C5 alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mutations in this gene cause complement component 5 deficiency, a disease characterized by recurrent bacterial infections. Alternative splicing results in multiple transcript variants.
- Overview
- Humanized Anti-C5 IgG2/G4-kappa antibody (Clone 1)
- Species Reactivity
- Human
- Name
- iFluor® 460 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 468/493
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS8272. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-730 | Anti-C5 (Eculizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-731 | Anti-C5 (Eculizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-735 | Anti-C5 (Pexelizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-728 | Anti-C5 (Eculizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-732 | Anti-C5 (Eculizumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-ITGA2B MAb (Clone 2)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2906)
- Anti-C. diff Toxin A MAb (Clone 3)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS3119)
- Anti-CD4 MAb (Clone 28)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4237)
- Anti-TPBG MAb (Clone 4)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS4935)
- Panitumumab-iFluor 680 (CAT#: ADC-FL-1162)
- Anti-TNFRSF10B MAb (Clone 2)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS14550)
- Anti-CD19 MAb (Clone 27)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS13237)
- Anti-IFNA1 MAb (Clone 5)-iFluor® 555 Succinimidyl Ester (CAT#: WJY0-LS16657)
- Anti-FGFR2 MAb (Clone 17)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2402)
- Anti-VEGFA MAb (Clone 5)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS9234)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
