Anti-CDH3 MAb (Clone 1)-iFluor® 546 Succinimidyl Ester (WJY0-LS14183)

This product is comprised of an Chimeric Anti-CDH3 antibody (Clone 1) labeled with iFluor® 546 Succinimidyl Ester. iFluor® 546 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

TARGET

Name
CDH3

Alternative Names
CDH3; CDHP; HJMD; PCAD; cadherin 3

Overview
Cadherin-3, also known as P-Cadherin, is a protein encoded by the CDH3 gene in humans. This gene is a classic cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein consisting of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in the hexacadherin cluster in a region on the long arm of chromosome 16, which is related to the loss of heterozygous events in breast and prostate cancer. In addition, abnormal expression of this protein was observed in cervical adenocarcinoma.

ANTIBODY

Overview
Chimeric Anti-CDH3 antibody (Clone 1)

Species Reactivity
Human

DYE

Name
iFluor® 546 Succinimidyl Ester

Color
Green

Excitation⁄Emission (nm)
541/557

Detection method
Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

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