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Anti-FAP MAb (Clone 3)-iFluor® 430 Succinimidyl Ester (CAT#: WJY0-LS4143)

This product is comprised of an Humanized Anti-FAP IgG1-kappa (Clone 3) labeled with iFluor® 430 Succinimidyl Ester. iFluor® 430 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

  • TARGET
  • ANTIBODY
  • DYE
  • Name
  • FAP
  • Alternative Names
  • FAP; fibroblast activation protein; alpha; seprase; DPPIV; integral membrane serine protease; 170 kDa melanoma membrane-bound gelatinase; FAPA; DKFZp686G13158;
  • Overview
  • The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Overview
  • Humanized Anti-FAP IgG1-kappa (Clone 3)
  • Species Reactivity
  • Human
  • Name
  • iFluor® 430 Succinimidyl Ester
  • Color
  • Green
  • Excitation⁄Emission (nm)
  • 433/498
  • Detection method
  • Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

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ADC-W-1134 Anti-FAP (Sibrotuzumab)-MC-Vc-PAB-SN38 ADC MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) SN-38 (7-ethyl-10-hydroxycamptothecin)
ADC-W-1131 Anti-FAP (Sibrotuzumab)-SPDB-DM4 ADC SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)

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