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- Anti-HGF MAb (Clone 6)-iFluor® 488 Succinimidyl Ester
Anti-HGF MAb (Clone 6)-iFluor® 488 Succinimidyl Ester (CAT#: WJY0-LS10496)
- TARGET
- ANTIBODY
- DYE
- Name
- HGF
- Alternative Names
- HGF; hepatocyte growth factor (hepapoietin A; scatter factor); deafness; autosomal recessive 39 ; DFNB39; hepatocyte growth factor; F TCF; fibroblast derived tumor cytotoxic factor; hepatopoietin A; HGFB; HPTA; lung fibroblast derived mitogen;
- Overview
- This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.
- Overview
- Humanized Anti-HGF IgG4-kappa (Clone 6)
- Species Reactivity
- Human
- Name
- iFluor® 488 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 491/516
- Detection method
- Fluorescent
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1188 | Anti-HGF (Rilotumumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-1187 | Anti-HGF (Rilotumumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1195 | Anti-HGF (Flanvotumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1199 | Anti-HGF (Ficlatuzumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1197 | Anti-HGF (Ficlatuzumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
For Research Use Only. NOT FOR CLINICAL USE.
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