- Home
- Products
- Customized FluoroAb™
- IL23A
- Anti-IL23A MAb (Clone 5)-iFluor® 440 Succinimidyl Ester
Anti-IL23A MAb (Clone 5)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS5946)
This product is comprised of an Humanized Anti-IL23A IgG4-kappa (Clone 5) labeled with iFluor® 440 Succinimidyl Ester. iFluor® 440 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- IL23A
- Alternative Names
- IL23A; IL-23; IL-23A; IL23P19; P19; SGRF; Interleukin 23; interleukin 23 subunit alpha
- Overview
- IL-23 is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration into tumours. IL-23 mediates its effects on both innate and adaptive arms of the immune system that express the IL-23 receptor. Th17 cells represent the most prominent T cell subset that responds to IL-23, although IL-23 has been implicated in inhibiting the development of regulatory T cell development in the intestine. Th17 cells produce IL-17, a proinflammatory cytokine that enhances T cell priming and stimulates the production of other proinflammatory molecules such as IL-1, IL-6, TNF-alpha, NOS-2, and chemokines resulting in inflammation.
- Overview
- Humanized Anti-IL23A IgG4-kappa (Clone 5)
- Species Reactivity
- Human
- Name
- iFluor® 440 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 434/480
- Detection method
- Fluorescent
Published Data
+ Submit Publications
Scientific Resources
Customer Reviews and FAQs
There are currently no Customer reviews or questions for WJY0-LS5946. Click the button above to contact us or submit your feedback about this product.
Quick Links
Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1351 | Anti-IL23A (Guselkumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1352 | Anti-IL23A (Tildrakizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1349 | Anti-IL23A (Guselkumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1347 | Anti-IL23A (Guselkumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1355 | Anti-IL23A (Tildrakizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
For Research Use Only. NOT FOR CLINICAL USE.
Related Products
- Anti-CSF2 MAb (Clone 1)-iFluor® 514 Succinimidyl Ester (CAT#: WJY0-LS10961)
- Anti-FAP MAb (Clone 1)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS217)
- Blinatumomab-iFluor 750 (CAT#: ADC-FL-389)
- Anti-CD6 MAb (Clone 1)-iFluor® 460 Succinimidyl Ester (CAT#: WJY0-LS7878)
- Anti-CD40 MAb (Clone 5)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2713)
- Anti-LTA MAb (Clone 3)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS1383)
- Anti-Thrombin inhibitor (BIBR_953) MAb (Clone 2)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS3178)
- Anti-CD70 MAb (Clone 8)-iFluor® 532 Succinimidyl Ester (CAT#: WJY0-LS12776)
- Anti-TNFSF13B MAb (Clone 2)-iFluor® 440 Succinimidyl Ester (CAT#: WJY0-LS4732)
- Anti-191P4D12 MAb (Clone 1)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS1804)
Online Inquiry
Welcome! For price inquiries, please feel free to contact us through the form on the left side. We will get back to you as soon as possible.
