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- Anti-IL5 MAb (Clone 4)-iFluor® 546 Succinimidyl Ester
Anti-IL5 MAb (Clone 4)-iFluor® 546 Succinimidyl Ester (CAT#: WJY0-LS15186)
- TARGET
- ANTIBODY
- DYE
- Name
- IL5
- Alternative Names
- Eosinophil differentiation factor; EDF; IL-5; TRF; T-cell replacing factor; B-cell differentiation factor I; Interleukin-5
- Overview
- This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
- Overview
- Humanized Anti-IL5 IgG1-kappa (Clone 4)
- Species Reactivity
- Human
- Name
- iFluor® 546 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 541/557
- Detection method
- Fluorescent
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-1390 | Anti-IL5 (Crenezumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1399 | Anti-IL5 (Reslizumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-1389 | Anti-IL5 (Crenezumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1395 | Anti-IL5 (Reslizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1397 | Anti-IL5 (Reslizumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
For Research Use Only. NOT FOR CLINICAL USE.
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