Anti-ITGAV MAb (Clone 2)-iFluor® 514 Succinimidyl Ester (WJY0-LS11199)

This product is comprised of an Humanized Anti-ITGAV lgG1 Antibody (Clone 2) labeled with iFluor® 514 Succinimidyl Ester. iFluor® 514 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.

TARGET

Name
ITGAV

Alternative Names
ITGAV; CD51; MSK8; VNRA; VTNR; integrin subunit alpha V

Overview
ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.

ANTIBODY

Overview
Humanized Anti-ITGAV lgG1 Antibody (Clone 2)

Species Reactivity
Human

DYE

Name
iFluor® 514 Succinimidyl Ester

Color
Green

Excitation⁄Emission (nm)
511/527

Detection method
Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

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