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- Anti-ITGAV MAb (Clone 4)-iFluor® 450 Succinimidyl Ester
Anti-ITGAV MAb (Clone 4)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS6952)
- TARGET
- ANTIBODY
- DYE
- Name
- ITGAV
- Alternative Names
- ITGAV; CD51; MSK8; VNRA; VTNR; integrin subunit alpha V
- Overview
- ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction.
- Overview
- Humanized Anti-ITGAV IgG2-kappa antibody (Clone 4)
- Species Reactivity
- Human
- Name
- iFluor® 450 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 451/502
- Detection method
- Fluorescent
Published Data
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Other Products
Same Target
| CAT# | Product Name | Linker | Payload |
| ADC-W-2440 | Anti-ITGAV (Abituzumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1492 | Anti-ITGAV (Intetumumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1494 | Anti-ITGAV (Intetumumab)-MC-Vc-PAB-SN38 ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | SN-38 (7-ethyl-10-hydroxycamptothecin) |
| ADC-W-2441 | Anti-ITGAV (Abituzumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-1495 | Anti-ITGAV (Intetumumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
For Research Use Only. NOT FOR CLINICAL USE.
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