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- Anti-KDR MAb (Clone 5)-iFluor® 405 Succinimidyl Ester
Anti-KDR MAb (Clone 5)-iFluor® 405 Succinimidyl Ester (CAT#: WJY0-LS2552)
- TARGET
- ANTIBODY
- DYE
- Name
- KDR
- Alternative Names
- FLK1; VEGFR; CD antigen CD309; FLK-1; Fetal liver kinase 1; VEGFR2; Vascular endothelial growth factor receptor 2; VEGFR-2; CD309; Kinase insert domain receptor; EC 2.7.10.1; Protein-tyrosine kinase receptor flk-1; KDR
- Overview
- Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
- Overview
- Humanized Anti-KDR IgG1-lambda (Clone 5)
- Species Reactivity
- Human
- Name
- iFluor® 405 Succinimidyl Ester
- Color
- Blue
- Excitation⁄Emission (nm)
- 403/427
- Detection method
- Fluorescent
Published Data
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| CAT# | Product Name | Linker | Payload |
| ADC-W-1521 | Anti-KDR (Alacizumab pegol)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1519 | Anti-KDR (Ramucirumab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC | MC-Vc-PAB-DMEA-(PEG2) | duocarmycin SA |
| ADC-W-584 | Anti-KDR-SPDP-NCS ADC | SPDP(N-succinimidyl 3-[2-pyridyldithio]-propionate) | NCS |
| ADC-W-1516 | Anti-KDR (Ramucirumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1520 | Anti-KDR (Alacizumab pegol)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
For Research Use Only. NOT FOR CLINICAL USE.
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